Are you looking for an alternative treatment for
Tinnitus? Antioxidant therapy has shown promise but most insurance plans will not cover the costs of this.
Have you ever thought of starting with nutrition? Eating a diet rich in high quality veggies and fruit with proper supplementation can prevent, reverse, or reduce
tinnitus.
Some hearing lose, such as tinnius, has been linked to oxidative stress. O
xygen is vital to living, but is also a
double-edged sword. While oxygen is necessary to sustain life, too much
oxygen in the body’s cells can lead to the production of Reactive Oxygen
Species (ROS) molecules. Untold damage is caused to the body by ROS,
which we normally refer to as “free radicals”. These dangerous molecules
are one of the leading causes of age related disease, being directly
responsible for over 100 human diseases including many types of cancer.
Free radicals are produced in normal metabolism when oxygen is used
to burn food for energy. They are also produced in certain disease
states and in response to environmental pollution and toxins. A free
radical is a molecule with an unpaired electron. This makes the molecule
unstable and highly reactive, trying to capture an electron that will
stabilize it. By capturing electrons from nearby molecules, the free
radical converts other molecules to free radicals, thereby initiating a
destructive chain reaction.
By producing oxidative damage in DNA, free radicals produce mutations
that, over time, can lead to hearing loss. Oxidative damage begins at birth
and is a cumulative risk factor for aging and disease. Stress,
infections, inflammation and exposure to pollutants and sunlight all
produce free radicals.
Supplements To Help Fight Tinnitus
Cellgevity™ is a powerful antioxidant and anti-inflammatory supplement, designed to significantly increase glutathione production in every cell of the body.
Cellgevity
is ideal for supporting lung function, reducing inflammation,
detoxifying the liver, strengthening the immune system, boosting energy
levels and for improving overall health.
All Natural Ingredients
Cellgevity contains a specially formulated blend of powerful natural ingredients:
- RiboCeine™ is a
unique combination of ribose and cysteine that enables the cells to
increase intracellular production of glutathione and ATP (energy).
- Selenium assists with the production of glutathione
- Curcumin (derived from the purest grade of turmeric) has anti-inflammatory properties and may help to modulate the CFTR defect. Read more about curcumin.
- Alpha Lipoic Acid is a potent antioxidant that supports the formation of glutathione
- Milk Thistle (silymarin) supports a healthy liver by removing harmful toxins
- Broccoli seed extract (sulforaphane) is a phytochemical that stimulates the cells to protect themselves against disease
- Grape seed extract contains polyphenols to help reduce inflammation
- Resveratrol
(found in the skin of grapes) is often called the "longevity molecule"
because of its beneficial cardiovascular effects, anti-cancer,
anti-inflammatory and anti-diabetic properties.
- Quercetin is a supporting flavonoid compound that scavenges free radicals in the body
- Bioperine stimulates the digestion and enhance absorption of nutrients
- Aloe extract supports a healthy immune system
- Vitamin C is involved in the production and recycling of glutathione
- Cordiceps
(derived from wild mushroom) has been highly valued in Chinese medicine
for centuries for its activity in restoring energy, increasing stamina,
promoting longevity and improving quality of life.
To fight tinnitus properly requires a very high nutritional demands and with the poor quality of our food today you will need help getting all the nutrients in. Max N-Fuze™ uses
advanced nanofusion technology to provide bio-available vitamins and
minerals that are easily absorbed, so that your body can achieve optimal
cellular function. Max N-Fuze is an easy to take liquid supplement that
works together with Cellgevity to help increase glutathione levels and strengthen your antioxidant defense system.
Max N-Fuze provides
the key vitamins, nutrients and antioxidants required for optimal
health, in an easy to take liquid supplement. A single one-ounce serving
of Max N-Fuze provides the same vitamins and nutrients as:
- The vitamin B-6 of 70 eggs
- The vitamin C of 2 lemons
- The vitamin A of 1 cup of spinach
- The vitamin B-6 of 5 lbs. of raw cauliflower
- The vitamin B-2 of 1 cup of almonds
- The folate of 30 spears of asparagus
- The selenium of 3 lbs. of raw tofu
- The manganese of 5 cups of garbanzo beans
|
- The vitamin E of 2 lbs. of avocados
- The vitamin D of 10 glasses of milk
- The vitamin B-1 of 150 cloves of garlic
- The vitamin B-12 of 3 gallons of yogurt
- The niacin of 5 large potatoes
- The biotin of 5 cups of Swiss chard
- The zinc of 2 cups of green peas
|
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Eating To Fight Tinnitus
(from
http://www.tinnitusformula.com/libraryd-tinnitus/diet-an/)
Have you ever noticed that some days your tinnitus
seems to worsen for no reason? Did you pause to think about what you ate
recently? I have learned when I have a salty meal my tinnitus gets
worse for several hours. The next day it will improve, providing I
haven’t taken more excess salt.
Maintaining a very good diet is critical in the management and
lowering of tinnitus sounds. Many foods affect tinnitus, both positively
and negatively, and it is important to understand which foods to avoid
and which ones to consume. In past articles we have discussed various
aspects of diet and tinnitus but have not put it all together in one
article, which is what I intend to do here.
Michael Seidman, MD is one of the foremost tinnitus specialists in
the US and endorses the use of antioxidant rich diet for managing
tinnitus. Dr. Seidman has known for years that it is imperative that
people who suffer from tinnitus consume a very good diet. He has always
stressed the need to reduce or eliminate their use of
salt, simple
sugars, saturated and trans-fats, nicotine, caffeine and alcohol. I
realize that for many of us that this is easier said than done.
I will go a step further and say that people who suffer from tinnitus
should reduce or eliminate consumption of fast foods and pre-packaged
or processed foods. This is due to the addition of large amounts of
salt, saturated fats, flavor enhancers and other chemicals meant to
prolong shelf-life or enhance the flavor and appearance of the products.
These chemicals are not food and have many undesirable side-effects.
For the most part they will negatively affect tinnitus and make it
louder.
So how do we change our diet to a healthier regimen? One bite at a
time. Becoming aware of what you eat is the first step to making better
choices. The following are not absolute dietary rules but guidelines to
understanding how diet affects tinnitus. No one, least of all me,
consumes a perfectly healthy diet. However, being aware of these
guidelines and incorporating them into our diet will improve overall
health and reduce tinnitus.
Generally speaking, anything that improves health also improves
tinnitus. People with high blood pressure will improve after the
pressure is lowered, people with high cholesterol will have improvement
when it comes under control. Very typically, people who are overweight
will have improvement after the extra pounds are shed.
Salt
Salt has an immediate effect on tinnitus and always makes it
worse. Excess salt restricts blood vessels, increases blood pressure and
reduces blood flow into the ears, eyes and brain. Increased blood
pressure is directly linked to increased tinnitus. I speak with many
people who are beset with serious tinnitus but don’t make the connection
between blood pressure and tinnitus loudness. Many of these people will
chow down on chips and other salty snacks, at the same time bemoaning
the ringing in their ears. When salt intake is reduced, many of these
same people report a lessening of tinnitus sounds.
There are high levels of salt in most processed and pre-packaged
foods. A can of soup contains more sodium than the recommended daily
allowance for an adult person. This is a primary reason to be very
careful of these products.
Sugar
Sugar metabolism has an important role to play in the proper
functioning of the auditory system. The brain and auditory system have
no inherent food supply. They are completely dependent on the regular
delivery of oxygen and glucose (sugar) from the blood supply. When this
supply of nutrients is disturbed or interrupted, imbalance and damage
can occur.
Studies have shown that 84% to 92% of people with tinnitus have a
sugar metabolism disorder known as hyperinsulinemia. This is
characterized by increased levels of insulin in the bloodstream. In and
of itself, this is not a dangerous condition. However, it is the first
step in the long slippery path to Type II Diabetes. Hyperinsulinemia
occurs because the body becomes insensitive to insulin and ineffective
in delivering sugar to the cells, where it is needed. Therefore the
pancreas produces more and more insulin in order to process blood sugar.
Researchers at the Federal University in Brazil conducted a clinical
study by treating tinnitus patients with a diet suitable for diabetics.
For a period of two years they were instructed to eat every three hours
to prevent hypoglycemia; to avoid refined sugar and simple
carbohydrates; to restrict their intake of fatty foods, especially
saturated or hydrogenated fats; to take no more than 2 cups of coffee
per day, limit intake of alcoholic beverages and drink four to six
glasses of water per day. At the end of the study, 76% of the
participants who observed the diet had improvement ranging from moderate
to complete resolution of their tinnitus.
An article with a complete discussion of this study is at
How Sugar Metabolism Affects Tinnitus.
Sugar Substitutes
So, refined sugar and simple carbohydrates are something that should be
avoided by people with tinnitus. The bad news is that many sugar
substitutes are worse than sugar itself. One of the worst is Aspartame,
which is used in many diet colas and other diet foods. It is sold under
the trade names NutraSweet, Equal, Spoonful and Indulge.
Aspartame,
along with Glutamate, is an excitatory neuro-transmitter in the brain.
It causes neurons to fire repeatedly until they become depleted and die.
This causes untold damage to the nervous system and can lead to
neuro-degenerative conditions including tinnitus. The complete story is
at
Neurotoxins and Tinnitus – Part 1.
Furthermore, Aspartame does not seem to lead to weight loss. Instead,
it creates a craving for sweets and carbohydrates which more than makes
up for the sugar that is not consumed. When people stop drinking diet
sodas, they typically lose weight.
Natural sugars found in fruits and vegetables are perfectly safe and
nutritious. Natural, unrefined sugars take longer to digest and do not
provide a sugar rush to the bloodstream that triggers excess insulin
production. Stevia and Xylitol are two natural sweeteners that are low
on the glycemic index and are safe for diabetics. They can generally be
found in health food stores.
Flavor Enhancers
Most processed, pre-packaged foods contain flavor enhancers that make
the food taste better. The primary flavor enhancer used by the food
industry is Monosodium Glutamate (MSG). MSG breaks down to Glutamate in
the body. Glutamate, like Aspartame, is an excitatory neuro-transmitter
that triggers neurons to fire until they become depleted and die. In
fact, for many of us, Glutamate is the primary villain causing our
tinnitus.
When hearing hair cells in the cochlea are damaged, by noise
exposure, ototoxic medications, infection or many other causes, they
release excess amounts of Glutamate. This Glutamate floods the
neuro-receptors in the auditory pathway and excites them to the point
where they fire continuously. During the course of neuron death,
tremendous amounts of free radicals are released which continue the
damage to the neurons. This type of tinnitus known as Cochlear-Synaptic
Tinnitus is the exact condition experienced by those of us with hearing
loss and tinnitus.
The
manufacturers of MSG have a long and checkered past with the United
States Food and Drug Administration. MSG has long been liberally used in
Chinese food. During the 1960’s there was an outbreak of sickness from
people eating in Chinese restaurants. There was actually quite a bit of
publicity about “Chinese Restaurant Syndrome” which was characterized by
sudden onset of headache, heartburn, palpitations, sweating, swelling,
and flushing of the face. MSG was getting a bad reputation and people
were staying away from it.
However, through a loophole in FDA labeling laws, MSG only has to be
listed on a label if it is added in its free form. If it is combined
with other additives it does not have to be listed. Now there are about
20 widely used food additives that contain MSG but don’t list it on the
label. These additives include hydrolyzed vegetable protein, vegetable
or plant protein, natural flavoring, spices and many others. The
complete story on MSG and food additives that incorporate it can be seen
at
Neurotoxins and Tinnitus – Part 2.
Fats
Saturated and trans-fats have multiple negative effects on the
body and tinnitus. Saturated fats are not recommended for those with
diabetes or hyperinsulinemia. They also increase bad cholesterol (LDL),
decrease good cholesterol (HDL), increase triglycerides and lead to
atherosclerosis. Atherosclerosis is not only a risk factor in heart
disease and stroke but also significantly reduces blood flow. People
with tinnitus need to increase blood flow to the inner ear to remove
toxins and maintain healthy cells. Tinnitus, in fact, can be caused by
nothing more than decreased blood flow to the inner ear.
Unsaturated
fats from vegetables, nuts and fish are very healthful. These fats are
necessary for life; they lower undesirable cholesterol levels, lower
blood pressure, reduce inflammation and are energy sources for the
brain. Cooking oils such as olive oil are widely used in the
Mediterranean area, noted for its low incidence of heart disease.
Omega 3 fatty acids found in fish oil have been shown to reduce
inflammation and pain. They act as anti-depressants and are helpful for
regulating mood. They increase insulin sensitivity and are helpful for
people with diabetes and hyperinsulinemia. The list of health benefits
of fish oil is very long. The complete story can be seen at
Inflammation, Omega-3’s and Tinnitus.
Mediterranean Diet
The best diet to consume, for all people as well as those of us
with tinnitus, consists of whole, freshly prepared foods, plenty of
fruits and vegetables, whole grains, beans and nuts. This diet is laid
out nicely in what has popularly become known as the “Mediterranean
Diet”. This diet recommends daily physical exercise. It employs plenty
of whole grained bread or pasta, fruits, vegetables, olive oil, cheese
and yogurt on a daily basis. Several times a week fish, poultry eggs and
sweets and several times a month red meat is consumed. It also allows
for wine in moderation.
A healthy diet is not difficult; in fact, it is very simple. A
general rule of thumb is the closer to its original state the food is
when consumed, the better it is for us. Conversely, the more processed
and changed to food is, the more we must exercise caution and restraint.
The best part of this is that fresh food tastes much better than
processed food.
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Supporting and Related Information On Antioxidants and Tinnitus
Antioxidants
Antioxidants are compounds that have the ability to neutralize
damaging reactive oxygen species (ROS). Since ROS are involved in the
development and progression of tinnitus and hearing loss, antioxidants
represent a promising therapeutic strategy (Sergi 2004; Savastano 2007;
Joachims 2003).
N-acetyl cysteine. N-acetyl
cysteine (NAC) is a naturally occurring antioxidant that has been used
for years to treat acetaminophen overdose and break up mucus; it also
increases the production of glutathione, one of the most prevalent
antioxidants in the body (Kopke 2007). NAC has been studied as a
potential therapeutic agent to protect hair cells from damage due to
excessive noise as well. A 2011 study on military recruits found that
NAC was able to protect the cochlea from damage due to noise from firing
a gun in an enclosed space (Lindblad 2011). Animal studies have also
found that NAC has a protective effect against continuous loud noises
(Lorito 2006; Bielefeld 2007) as well as impulse noise (Kopke 2005).
Another animal study showed that NAC may reduce noise-induced hearing
loss even when administered after exposure to dangerous levels of noise
(Coleman 2007). NAC has generated interest in the field of hearing loss
because it is safe for human consumption and has already been approved
for some uses in humans (e.g., treatment of acetaminophen toxicity)
(Kopke 2007).
Acetyl-L-carnitine. Mitochondria
are the energy powerplants of the cell. They are also the site of ROS
production, especially when the cell is under stress. In cochlear hair
cells, mutations in mitochondrial DNA and declining function of the
mitochondria have been found to cause age-induced hearing loss (Yamasoba
2007). As a result, compounds that help maintain mitochondrial health,
such as acetyl-L-carnitine, may help protect cells from damage. Animal
studies have found that acetyl-L-carnitine is able to protect the
cochlea from both continuous and impulse noise damage as well as prevent
loss of hair cells (Kopke 2002; Kopke 2005). Acetyl-L-carnitine was
also found to reduce mutations in mitochondrial DNA, suggesting that it
could prevent not only noise-induced hearing loss, but also age-related
hearing loss (Seidman 2000). Much like NAC, acetyl-L-carnitine appears
to be effective even when administered after exposure to loud noise(s)
(Coleman 2007; Du 2012). In one animal study, acetyl-L-carnitine was
shown to protect against ototoxicity induced by the chemotherapeutic
drug cisplatin (Gunes 2011).
Lipoic acid. Lipoic acid has been
found to reduce age-related hearing loss (Seidman 2000). Preliminary
animal studies have also found that lipoic acid can help protect against
noise-induced hearing loss and preserve inner-ear mitochondrial
function (Diao 2003; Peng 2010). This may be partly due to the effect it
has on glutathione (i.e., a naturally occurring antioxidant in the
body). Studies have found increasing glutathione levels help protect the
cochlea from damage due to loud noises (Le Prell 2007). In one
laboratory study, lipoic acid was shown to increase glutathione levels
in nerve cells, protecting them from damage (Jia 2008). Lipoic acid may
also be able to counteract the action of toxins (e.g., carbon monoxide)
that aggravate the effects of noise and make normally safe levels of
volume harmful to the ear (Pouyatos 2008). In a clinical trial among 46
elderly subjects with hearing loss, 8 weeks of treatment with lipoic
acid (60 mg/day) combined with two other free radical scavengers
(vitamin C [600 mg/day] and rebamipide [300 mg/day]) significantly
improved hearing at all frequencies tested (Takumida 2009).
Vitamins. Dietary supplementation
with vitamins that have antioxidant capabilities can help protect the
hair cells of the cochlea. One animal study showed that a 35-day
pretreatment regimen of vitamin C may be able to protect against
noise-induced hearing loss (McFadden 2005). Similarly, supplementing
animals with certain forms of vitamins A and E have shown significant
protective effects (Hou 2003; Ahn 2005). The length of time vitamins
need to be taken prior to noise exposure may vary depending on the
vitamin. For example, vitamin E appears to be effective with three days
of pretreatment, vitamin A may only require two days to be effective,
and Vitamin C may require a longer pretreatment period. In addition,
taking vitamins in combination may be more effective than any one of
them alone (Le Prell 2007). For example, a combination of B-vitamins,
vitamins C & E, and L-carnitine protected rodents from cisplatin
ototoxicity (Tokgoz 2012).
Folate and Vitamin B12. Folate and
vitamin B12 are important for the functioning of many cells in the
body, including nerve cells. They also help reduce levels of
homocysteine, a potentially toxic compound found in the body. Elevated
homocysteine levels are linked to an increased risk of hearing problems
(Gok 2004; Gopinath 2010). Vitamin B12 injections (1 mg for 7 days
followed by 5 mg on day 8) protected against noise-induced hearing loss
in healthy volunteers aged 20 to 30 years (Quaranta 2004). Researchers
have found that patients with low levels of folate in their blood are
more likely to develop hearing loss (Gok 2004; Lasisi 2010; Gopinath
2010), and that low vitamin B12 levels are associated with hearing loss
(Gok 2004) and tinnitus (Shemesh 1993).
Magnesium. Because loud noise
impairs blood flow to the cochlea, researchers have also examined
compounds that could help improve circulation to the hair cells and
prevent their death. Magnesium is known to help expand blood vessels and
improve circulation; it also helps control the release of glutamate,
one of the major contributors to noise-induced hearing loss (Le Prell
2011). Animal studies have found that magnesium deficiency increases the
risk of noise-induced hearing loss (Sendowski 2006b; Scheibe 2002). A
combination of magnesium and other antioxidants may synergistically
prevent hearing loss, potentially because magnesium’s ability to
increase blood flow also helps transport the protective antioxidants (Le
Prell 2011). Other animal studies have determined that magnesium can
protect against impulse noise damage (Sendowski 2006a; Haupt 2003).
Magnesium’s benefits have been demonstrated in human trials as well;
magnesium supplementation (122 mg daily for ten days) reduced
noise-induced hearing loss in men aged 16-37 years (Attias 2004).
Studies have also found that both intravenous magnesium and oral
magnesium supplementation may be beneficial for other types of hearing
loss, such as sudden sensorineural hearing loss (Gordin 2002; Coates
2010).
Melatonin. Melatonin, a hormone
critical for healthy sleep (Wurtman 2012), has powerful antioxidant
properties. Animal studies have found that it is effective at preventing
hearing damage after exposure to loud noises (Karlidag 2002; Bas 2009).
It is also effective at treating other types of hearing loss caused by
ROS, such as due to the chemotherapy drug cisplatin (Lopez-Gonzalez
2000). Researchers have discussed the potential for melatonin to act as a
protectant against age-related hearing loss (Martinez 2009). For
example, it was noted in a study that low plasma levels of melatonin
were associated with significant high-frequency hearing loss among
elderly subjects (Lasisi 2011).
Additionally, melatonin has been tested as a treatment for tinnitus,
both in combination with the medication sulpiride (an atypical
antipsychotic) and on its own. On its own, melatonin provides relief
from tinnitus, especially in people with significant sleep problems
(Rosenberg 1998; Megwalu 2006; Reiter 2011).When combined with
sulpiride, melatonin reduces the perception of tinnitus by diminishing
the activity of dopamine, a chemical in the brain. In one study,
sulpiride alone relieved tinnitus in 56% of subjects while melatonin
alone reduced tinnitus in 40%. However, when used together, 81% of
subjects reported relief from their tinnitus symptoms (Lopez-Gonzalez
2007).
Ginkgo Biloba. Ginkgo biloba, a
commonly used herbal supplement, has attracted interest as a means of
protecting against hearing loss as well as a treatment for tinnitus.
Early animal studies found that when a standardized preparation of
Ginkgo biloba extract was given as a supplement to animals, it reduced
behavioral manifestations of tinnitus (Jastreboff 1997). This extract,
at a dose of 160 mg daily over a 12 week period, was also effective at
reducing symptoms in humans (Morgenstern 2002). However, other studies
have found negligible or no effect (Hilton 2010; Canis 2011); therefore,
more research is needed in this area. Ginkgo biloba may also be
effective at preventing hearing loss that causes tinnitus; an animal
study found that a Gingko biloba extract was able to reduce drug-induced
oxidative damage to hair cells in the cochlea (Yang 2011).
Coenzyme Q10. Coenzyme Q10(CoQ10)
supports mitochondrial function and has significant antioxidant
properties (Quinzii 2010). Animal studies have found that
supplementation with CoQ10 reduced noise-induced hearing loss and the
death of hair cells (Hirose 2008; Fetoni 2009, 2012). Human studies have
also yielded promising results, as 160-600 mg of CoQ10 daily was found
to reduce hearing loss in people with sudden sensorineural hearing loss
and presbycusis (Ahn 2010; Salami 2010; Guastini 2011). Also, a small
preliminary trial found that CoQ10 supplementation alleviated tinnitus
in those whose CoQ10 blood levels were initially low (Khan 2007).
Another small trial found CoQ10 may slow progression of hearing loss
associated with a mitochondrial genetic mutation (Angeli 2005).
Zinc. Zinc, a mineral involved in
many physiological processes (including nervous system function), has
antioxidant and anti-inflammatory properties (Frederickson 2000; Prasad
2008). Evidence suggests that inadequate zinc intake may be associated
with impaired hearing (Kang 2012). Researchers have found that zinc
supplementation may be helpful in treating some forms of hearing loss
(Yang 2010). In addition, low levels of zinc correlate with perceived
loudness of tinnitus in afflicted individuals (Arda 2003).
Omega-3 fatty acids. Long-chain omega-3
(n-3) polyunsaturated fatty acids, long recognized as important for
health, may also affect hearing loss; a preliminary study found that
participants with the highest blood levels of these beneficial fats
suffered the least amount of hearing loss over time (Dullemeijer 2010).
In another study, greater fish or fish oil consumption was associated
with less hearing loss among nearly 3,000 subjects over 50 years of age.
The authors remarked that “dietary intervention with n-3 PUFAs could prevent or delay the development of age-related hearing loss” (Gopinath 2010).